Amino Acids, Nucleosides and Nucleotides

Amino Acids

We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.

Nucleosides and Nucleoside Phosphoramidites

We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.

Nucleotides

dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.

Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.

  • Amino Acids for Stapled Peptides
  • 2-Methylated Amino Acids
  • Peptide Labeling
  • Other Unnatural Amino Acids
  • Nucleosides
  • HNA Precursors
  • Morpholino Nucleosides
  • Nucleoside Phosphoramidites and Nucleotides
  • Peptide Labeling

    Structure Details
    Product Name: Fmoc-Lys(Dansyl)-OH
    Order number: 204489
    CAS: 118584-90-0
    Purity: >=95%
    Appearance: solid
    MF: C33H35N3O6S
    MW: 601.718
    MP: n.a. oC

    Description:
    This Fmoc-protected solid-phase amenable amino acid carrying a fluorescent group Dansyl is a useful fluorescent peptide labeler for life sciences.
    Product Name: Fmoc- Lys(DABCYL)-OH
    Order number: 204492
    CAS: 146998-27-8
    Purity: >=95%
    Appearance: solid
    MF: C36H37N5O5
    MW: 619.722
    MP: n.a. oC

    Description:
    This Fmoc-protected solid-phase amenable amino acid carrying a fluorescent group Dabcyl is a useful peptide labeler for life sciences.
    Product Name: Fmoc-Lys(Biotin)-OH
    Order number: 204493
    CAS: 146987-10-2
    Purity: >=95%
    Appearance: solid
    MF: C31H38N4O6S
    MW: 594.727
    MP: n.a. oC

    Description:
    This Fmoc-protected solid-phase amenable amino acid carrying a biotinyl group is a valuable peptide labeler for life sciences.
    Product Name: N2-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N6-[2-(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-lysine
    Order number: 204419
    CAS: 386213-32-7
    Purity: >=95%
    Appearance: solid
    MF: C33H32N2O8
    MW: 584.625
    MP: n.a. oC

    Description:
    This is a valuable fluorescent to label peptide at N-terminal.
    Product Name: Fmoc-Lys(6`-FAM) -OH
    Order number: 204534
    CAS: 1266666-04-9
    Purity: >=95%
    Appearance: solid
    MF: C42H34N2O10
    MW: 726.738
    MP: n.a. oC

    Description:
    This Fmoc-protected lysine is used for fluoroscein labeling.
    Product Name: Fmoc-Lys(5`-FAM) -OH
    Order number: 204535
    CAS: 1242933-88-5
    Purity: >=95%
    Appearance: solid
    MF: C42H34N2O10
    MW: 726.738
    MP: n.a. oC

    Description:
    This Fmoc-protected lysine is used for fluoroscein labeling.