We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: Adenosine, N,N-bis[(1,1-diMethylethoxy)carbonyl]-2',3'-O-(1-Methylethylidene)- Order number: 211361 CAS: 1152172-19-4 Purity: 97% Appearance: n.a. MF: C23H33N5O8 MW: 507.5 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Uridine, 2'-deoxy-2'-fluoro-5-methyl- Order number: 211362 CAS: 122799-38-6 Purity: 98% Appearance: SOLID MF: C10H13FN2O5 MW: 260.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Guanosine, 3'-deoxy-3'-fluoro- Order number: 211363 CAS: 123402-21-1 Purity: 95% Appearance: WHITE POWDER MF: C10H12FN5O4 MW: 285.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Benzenepropanoic acid, 4-[2-[[6-amino-9-(N-ethyl-?-D-ribofuranuronamidosyl)-9H-purin-2-yl]amino]ethyl]-, hydrochloride (1:1) Order number: 211364 CAS: 124431-80-7 Purity: ?98(HPLC)% Appearance: SOLID MF: C23H30ClN7O6 MW: 536 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: D-Ribofuranose, 3-azido-3-deoxy-, 1,2-diacetate 5-(4-methylbenzoate) Order number: 211365 CAS: 120143-22-8 Purity: n.a.% Appearance: n.a. MF: C17H19N3O7 MW: 377.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: D-Ribofuranoside, methyl Order number: 211367 CAS: 13039-63-9 Purity: 97% Appearance: LIQUID MF: C6H12O5 MW: 164.2 MP: n.a. oC Description: This is a useful starting material for nucleoside chemistry. |