We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: ?-D-Ribofuranose, 1,5-bis(dihydrogen phosphate), tetrasodium salt (9CI) Order number: 211349 CAS: 113599-17-0 Purity: n.a.% Appearance: SOLID MF: MW: MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: Cytidine, N-acetyl-2'-O-methyl- Order number: 211350 CAS: 113886-71-8 Purity: 97% Appearance: SOLID MF: C12H17N3O6 MW: 299.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Cytidine, 5-methyl-2'-O-methyl- Order number: 211351 CAS: 113886-70-7 Purity: 97% Appearance: SOLID MF: C11H17N3O5 MW: 271.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Uridine 5'-(tetrahydrogen triphosphate), sodium salt, hydrate (1:3:2) Order number: 211352 CAS: 116295-90-0 Purity: ?98% Appearance: SOLID MF: C9H12N2O15P3--- MW: 481.1 MP: n.a. oC Description: This is a useful building block for biosynthesis of nucleic acids. |
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Product Name: Cytidine, 5-iodo- Order number: 211353 CAS: 1147-23-5 Purity: 98% Appearance: SOLID MF: C9H12IN3O5 MW: 369.1 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-N-(2-methyl-1-oxopropyl)- Order number: 211354 CAS: 114745-26-5 Purity: 97% Appearance: WHITE POWDER MF: C36H39N5O8 MW: 669.7 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |