We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] Order number: 211537 CAS: 104992-55-4 Purity: 97% Appearance: WHITE POWDER MF: C53H66N7O8PSi MW: 988.2 MP: n.a. oC Description: This is a useful building block for nucleotide synthesis on solid support. |
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Product Name: Adenosine triphosphate Order number: 211541 CAS: 56-65-5 Purity: 95% Appearance: SOLID MF: C10H16N5O13P3 MW: 507.2 MP: n.a. oC Description: This is a useful building block for biosynthesis of nucleic acids. |
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Product Name: 2?(3?)-O-(4-Benzoylbenzoyl)adenosine 5?-triphosphate triethylammonium salt Order number: 211546 CAS: 112898-15-4 Purity: 95% Appearance: WHITE CRYSTALLINE POWDER MF: C84H138N16O30P6 MW: 2038 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: Cytidine-5'-triphosphate disodium salt Order number: 211555 CAS: 36051-68-0 Purity: 98% Appearance: SOLID MF: C9H14N3Na2O14P3 MW: 527.1 MP: n.a. oC Description: This is a useful building block for biosynthesis of nucleic acids. |
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Product Name: Uridine 5'-(trihydrogen diphosphate), sodium salt Order number: 211558 CAS: 21931-53-3 Purity: 98% Appearance: SOLID MF: C9H11N2Na3O12P2 MW: 470.1 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: 2'-Deoxyguanosine-5'-monophosphoric acid disodium salt Order number: 211579 CAS: 33430-61-4 Purity: 98% Appearance: SOLID MF: C10H12N5Na2O7P MW: 391.2 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |