Amino Acids, Nucleosides and Nucleotides

Amino Acids

We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.

Nucleosides and Nucleoside Phosphoramidites

We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.

Nucleotides

dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.

Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.

  • Amino Acids for Stapled Peptides
  • 2-Methylated Amino Acids
  • Peptide Labeling
  • Other Unnatural Amino Acids
  • Nucleosides
  • HNA Precursors
  • Morpholino Nucleosides
  • Nucleoside Phosphoramidites and Nucleotides
  • Nucleoside Phosphoramidites and Nucleotides

    Structure Details
    Product Name: Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
    Order number: 211537
    CAS: 104992-55-4
    Purity: 97%
    Appearance: WHITE POWDER
    MF: C53H66N7O8PSi
    MW: 988.2
    MP: n.a. oC

    Description:
    This is a useful building block for nucleotide synthesis on solid support.
    Product Name: Adenosine triphosphate
    Order number: 211541
    CAS: 56-65-5
    Purity: 95%
    Appearance: SOLID
    MF: C10H16N5O13P3
    MW: 507.2
    MP: n.a. oC

    Description:
    This is a useful building block for biosynthesis of nucleic acids.
    Product Name: 2?(3?)-O-(4-Benzoylbenzoyl)adenosine 5?-triphosphate triethylammonium salt
    Order number: 211546
    CAS: 112898-15-4
    Purity: 95%
    Appearance: WHITE CRYSTALLINE POWDER
    MF: C84H138N16O30P6
    MW: 2038
    MP: n.a. oC

    Description:
    This is a useful material for nucleotide chemistry and biology.
    Product Name: Cytidine-5'-triphosphate disodium salt
    Order number: 211555
    CAS: 36051-68-0
    Purity: 98%
    Appearance: SOLID
    MF: C9H14N3Na2O14P3
    MW: 527.1
    MP: n.a. oC

    Description:
    This is a useful building block for biosynthesis of nucleic acids.
    Product Name: Uridine 5'-(trihydrogen diphosphate), sodium salt
    Order number: 211558
    CAS: 21931-53-3
    Purity: 98%
    Appearance: SOLID
    MF: C9H11N2Na3O12P2
    MW: 470.1
    MP: n.a. oC

    Description:
    This is a useful material for nucleotide chemistry and biology.
    Product Name: 2'-Deoxyguanosine-5'-monophosphoric acid disodium salt
    Order number: 211579
    CAS: 33430-61-4
    Purity: 98%
    Appearance: SOLID
    MF: C10H12N5Na2O7P
    MW: 391.2
    MP: n.a. oC

    Description:
    This is a useful material for nucleotide chemistry and biology.