We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: pseudo UTP Order number: 204803 CAS: 1175-34-4 Purity: 98% Appearance: solid MF: C9H12N2Na3O15P3 MW: 550.08 MP: n.a. oC Description: dNTP and NTP are widely used in PCR, cRNA synthesis, RCA, MDA, DNA labeling and sequencing, in vitro transcription, etc. |
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Product Name: Adenosine 5'-(trihydrogen diphosphate), compd. with cyclohexanamine (1:2) (9CI) Order number: 211340 CAS: 102029-87-8 Purity: 95% Appearance: SOLID MF: C22H41N7O10P2 MW: 625.5 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: ?-D-Ribofuranose, 1,5-bis(dihydrogen phosphate), tetrasodium salt (9CI) Order number: 211349 CAS: 113599-17-0 Purity: n.a.% Appearance: SOLID MF: MW: MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: Uridine 5'-(tetrahydrogen triphosphate), sodium salt, hydrate (1:3:2) Order number: 211352 CAS: 116295-90-0 Purity: ?98% Appearance: SOLID MF: C9H12N2O15P3--- MW: 481.1 MP: n.a. oC Description: This is a useful building block for biosynthesis of nucleic acids. |
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Product Name: 5'-Inosinic acid Order number: 211368 CAS: 131-99-7 Purity: 98% Appearance: SOLID MF: C10H13N4O8P MW: 348.2 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: 5'-Cytidylic acid, 2'-deoxy-, sodium salt (1:2) Order number: 211369 CAS: 13085-50-2 Purity: 98% Appearance: SOLID MF: C9H12N3Na2O7P MW: 351.2 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |