We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: 5'-DMT-Ac-rC Order number: 211679 CAS: 121058-82-0 Purity: 98% Appearance: n.a. MF: C32H33N3O8 MW: 587.6 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 5'-Uridylic acid,5-bromo- Order number: 211680 CAS: 2149-79-3 Purity: 98% Appearance: n.a. MF: C9H10BrN2O9P-- MW: 401.1 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: Sodium ((2R,3S,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl phosphate Order number: 211681 CAS: 42155-08-8 Purity: 98% Appearance: WHITE POWDER MF: C9H11N2Na2O8P MW: 352.1 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: N6-Ethenoadenosine Order number: 211682 CAS: 39007-51-7 Purity: n.a.% Appearance: SOLID MF: C12H13N5O4 MW: 291.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: adenosine 2':3'-cyclic monophosphate sodium salt Order number: 211683 CAS: 37063-35-7 Purity: n.a.% Appearance: SOLID MF: C10H11N5NaO6P MW: 351.2 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: 2-Amino-9-((3aR,4R,6R,6aR)-6-(hydroxymethyl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)-1H-purin-6(9H)-one Order number: 211684 CAS: 362-76-5 Purity: 95% Appearance: WHITE POWDER MF: C13H17N5O5 MW: 323.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |