We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: 1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione Order number: 211645 CAS: 951-78-0 Purity: ?99% Appearance: SOLID MF: C9H12N2O5 MW: 228.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Thymidine, 4-thio- Order number: 211646 CAS: 7236-57-9 Purity: n.a.% Appearance: SOLID MF: C10H14N2O4S MW: 258.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: ?, ?-Methyleneadenosine 5'-triphosphate disodium salt Order number: 211647 CAS: 7414-56-4 Purity: 97% Appearance: SOLID MF: C11H18N5Na2O12P3 MW: 551.2 MP: n.a. oC Description: This is a useful building block for biosynthesis of nucleic acids. |
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Product Name: Guanosine 3',5'-monophosphate Order number: 211648 CAS: 7665-99-8 Purity: ?98% Appearance: SOLID MF: C10H12N5O7P MW: 345.2 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: 1-(2-Deoxy-2-fluoro-b-D-arabinofuranosyl)uracil Order number: 211650 CAS: 69123-94-0 Purity: 95% Appearance: WHITE POWDER MF: C9H11FN2O5 MW: 246.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: alpha-nicotinamide adenine dinucleotide,alpha-diphosphopyri Order number: 211651 CAS: 7298-93-3 Purity: from Saccharomyces cerevisiae, ?1 -isomer, ?95% Appearance: n.a. MF: C21H27N7O14P2 MW: 663.4 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |