Technology
ABOUT US
W&J PharmaChem, Inc is a Maryland company providing high quality chemical products and synthesis services to support chemical and pharmaceutical development, and we operate under the US laws of business.
PRODUCT
Our products are listed in professional industrial product data-bases and, for the most part, available for dispatch. We are the original and proprietary source of some hard-to-find benzothiazoles, pyridines, nucleosides, amino acids and active pharmaceutical ingredients for research and commercial purposes.
While we pursue scientific rigor, we are equally serious on our commitment to product quality.
We apply same quality standards to our carefully selected partners through in-depth quality system qualification and business system evaluation.
CHEMISTRY
- We are capable of performing multi-step syntheses of complex molecules. Our strength is on stereo-controlled processes, metal catalyzed processes and nucleoside chemistry.
- On pilot and production scales, we focus on impurity control, safety and cost issues.
- Suzuki Coupling, 20-30 kg/batch
- Fischer-Indole Synthesis, 200 kg/batch
- Diazatization for Azo-coupling, 30-40 kg/batch
- Ullmann (Cu or Pd catalysis) Coupling, 100kg/batch
- Vilsmeier Reaction, 100kg/batch
- Fluorination, knowhow/equipment
- High Pressure Reactions: 200-250 kg/batch
ANALYTICAL CAPABILITY
- NMR (Brukers)
- LC/MS (Shimadzu)
- GC/MS (Shimadzu)
- HPLC (Waters & Shimadzu)
- GC (Varian & Shimadzu)
- FT-IR, UV (JASCO)
- DSC (Shimadzu)
- Analytical Balance (MettlerToledo)
- pH Meter (MettlerToledo)
REGULATORY COMPLIANCE
- Materials Management SOPs
- Specification and In Process Control SOPs
- Product Release QC/QA Control Flow Charts
- Documentation Management/Change Control SOP
- EHS SOP , Implementation Documents and Production Reports
- ICH Compliance and On-going Quality Improvement Program
DMF SUBMISSION
We prepare and evaluate drug master files and manage submission/registration logistics.